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Series GSE69084 Query DataSets for GSE69084
Status Public on Jul 01, 2016
Title Replication timing of control and suv4-20h (KO and inducible mutant) cells
Platform organism Homo sapiens
Sample organism Mus musculus
Experiment type Genome variation profiling by genome tiling array
Summary Although histone modifications have been implicated in many DNA-dependent processes, their precise role in DNA replication remains poorly understood. Here, we show that the regulation of histone H4-K20 methylation states, in particular for the trimethylation, is a critical determinant of licensing and time activation of replication origins in mammalian cells.
Overall design WT cells versus suv4-20h KO cells, and non-induced cells versus induced cells
Contributor(s) Brustel J, Dulev S, Kirstein N, Izard F, Grimaud C, Cayrou C, Schotta G, Mechali M, Baldacci G, Sardet C, Batada NN, Cadoret J, Schepers A, Julien E
Citation(s) 28778956
Submission date May 20, 2015
Last update date Jun 05, 2019
Contact name Jean-Charles Cadoret
Organization name CNRS/ Université de Paris
Street address 15 rue hélène Brion
City Paris
ZIP/Postal code 75013
Country France
Platforms (1)
GPL10123 Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version)
Samples (4)
GSM1692637 control MEF 362.2 replication timing
GSM1692638 KO suv4-20h replication timing
GSM1692639 Non-induced suv4-20h mutant replication timing
This SubSeries is part of SuperSeries:
GSE69085 Degree of H4-K20me defines distinct subsets of replication origins in active and silent chromatin domains of mammalian cells
BioProject PRJNA284498

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69084_RAW.tar 75.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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