GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE69075 Query DataSets for GSE69075
Status Public on May 21, 2015
Title Role of histone demethylase LSD1 in hepatic cancer metabolism
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Transcriptome analysis of LSD1-depleted HepG2 cells revealed that LSD1 regulates the expression of glycolytic and mitochondrial metabolism genes.
We found that LSD1 is an important regulator of glycolysis and mitochondrial respiration in hepatoma.
Overall design We depleted LSD1 in HepG2 human hepatoma cells using two different siRNAs, and then carried out an expression microarray experiment.
Contributor(s) Sakamoto A, Hino S, Nakao M
Citation(s) 25649769
Submission date May 20, 2015
Last update date Mar 25, 2019
Contact name Akihisa Sakamoto
Organization name Kumamoto University
Department Institute of Molecular Embryology and Genetics
Lab Department of Medical Cell Biology
Street address 2-2-1 Honjo, Chuo-ku
City Kumamoto
ZIP/Postal code 860-0811
Country Japan
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (4)
GSM1692555 Cont1
GSM1692556 Cont2
GSM1692557 LSD1-KD1
BioProject PRJNA284489

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69075_RAW.tar 17.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap