GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE69054 Query DataSets for GSE69054
Status Public on Aug 29, 2017
Title An Nfic-Hedgehog Signaling Cascade Regulates Tooth Root Development
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary This study aimed to perform transcriptome profiling of Nfic-/- and corresponding control tooth germ at root initiation stage to identify differentially expressed for key regulators of root development.
Coordination between the Hertwig’s Epithelial Root Sheath (HERS) and apical papilla (AP) is crucial for proper root development process. The Hedgehog (Hh) signaling pathway and Nfic are both involved in tooth root development.
Overall design mRNA profiling of apical half of tooth germ from 6 pairs of 4-day-old Nfic-/- and littermate Nfic+/- control mice were generated using Illumina Next-Seq 500
Contributor(s) Liu Y, Feng J, Li J, Zhao H, Liu Y, Ho T, Chai Y
Citation(s) 26293299
Submission date May 19, 2015
Last update date May 15, 2019
Contact name Vasu Punj
Organization name USC
Street address Biggy Street
City Los Angeles
State/province CA
ZIP/Postal code 90033
Country USA
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (12)
GSM1691588 YL-C-5
GSM1691589 YL-M-5
GSM1691590 YL-C-6
BioProject PRJNA284406
SRA SRP058506

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69054_RPKM_values.txt.gz 1.6 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap