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Status |
Public on Aug 17, 2015 |
Title |
Runx1- responsive genes in mdx muscles |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
RNA-seq was performed to compare expression pattern of musles taken form two mice strains- mdx and mdx/Runx1f/f, which are double KO carrting a muscle specific ablation of Runx1 using a Myf5-Cre. This comparison revealed the Runx1- responsive gene set in mdx muscles. we could cross this data with prior retrived datd from privous experiments found in this GEO quary, to pinpiont Runx1 target genes in muscle rgeneration
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Overall design |
RNA was extracted form soleus muscles of 2 months old mice, n=3,4 for mdx and mdx/Runx1f/f, respectively . Differentially expressed genes were discovered using the DeSeq2 software
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Contributor(s) |
Umansky K, Groner Y, Feldmesser E |
Citation(s) |
26697350 |
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Submission date |
May 18, 2015 |
Last update date |
Jul 31, 2019 |
Contact name |
kfir baruch Umansky |
E-mail(s) |
kfirum@weizmann.ac.il
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Phone |
97289342318
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Organization name |
Weizmann Institute
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Street address |
POB 25
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City |
Rehovot |
State/province |
Rehovot |
ZIP/Postal code |
76100 |
Country |
Israel |
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Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (7)
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This SubSeries is part of SuperSeries: |
GSE56131 |
Transcription factor Runx1 cooperates with MyoD and c-Jun to regulate the balance of myoblast proliferation/differentiation |
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Relations |
BioProject |
PRJNA284273 |
SRA |
SRP058454 |