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Series GSE68998 Query DataSets for GSE68998
Status Public on Aug 17, 2015
Title Runx1- responsive genes in mdx muscles
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary RNA-seq was performed to compare expression pattern of musles taken form two mice strains- mdx and mdx/Runx1f/f, which are double KO carrting a muscle specific ablation of Runx1 using a Myf5-Cre. This comparison revealed the Runx1- responsive gene set in mdx muscles. we could cross this data with prior retrived datd from privous experiments found in this GEO quary, to pinpiont Runx1 target genes in muscle rgeneration
Overall design RNA was extracted form soleus muscles of 2 months old mice, n=3,4 for mdx and mdx/Runx1f/f, respectively . Differentially expressed genes were discovered using the DeSeq2 software
Contributor(s) Umansky K, Groner Y, Feldmesser E
Citation(s) 26697350
Submission date May 18, 2015
Last update date Jul 31, 2019
Contact name kfir baruch Umansky
Phone 97289342318
Organization name Weizmann Institute
Street address POB 25
City Rehovot
State/province Rehovot
ZIP/Postal code 76100
Country Israel
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (7)
GSM1689878 mdx 1 (358)
GSM1689879 mdx 2 (361)
GSM1689880 mdx 3 (373)
This SubSeries is part of SuperSeries:
GSE56131 Transcription factor Runx1 cooperates with MyoD and c-Jun to regulate the balance of myoblast proliferation/differentiation
BioProject PRJNA284273
SRA SRP058454

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68998_DiffExpDeseq2_mdx2_NOut_3.6.14.csv.gz 2.1 Mb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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