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Series GSE68411 Query DataSets for GSE68411
Status Public on Feb 10, 2017
Title Identification and Differential Expression of MicroRNAs Associated with Fat Deposition in Wistar Rat Liver Using Solexa Sequencing
Organism Rattus norvegicus
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary we analyzed the miRNAs expression in Wistar rat liver tissues, High glucose (HG)-induced NAFLD Wistar rats (NAFLD group, n=3) and normal Wistar rats (normal group, n=3). Results provided the first global miRNAs in the NAFLD Wistar rat livers, and expanded the miRNAs repertoire in normal Wistar rat livers, which should be useful for further investigation into the biological functions and evolution of miRNAs in rats and other species. These findings suggest an important role of miRNAs in liver fat deposition, and implicate the participation of miRNAs in the NAFLD pathophysiological processes.
 
Overall design Total RNA obtained from isolated NAFLD Wistar rat liver tissues compared to normal Wistar rat liver tissues.
 
Contributor(s) Wang Z, Zhang D
Citation(s) 27331102
Submission date Apr 29, 2015
Last update date May 15, 2019
Contact name Yuqian Wang
E-mail(s) 739961322@qq.com
Organization name Shandong Agricultural University
Street address Daizong Street No. 61
City Taian
ZIP/Postal code 271000
Country China
 
Platforms (1)
GPL14844 Illumina HiSeq 2000 (Rattus norvegicus)
Samples (6)
GSM1671256 NAFLD 1
GSM1671257 NAFLD 2
GSM1671258 NAFLD 3
Relations
BioProject PRJNA282669
SRA SRP057805

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68411_RAW.tar 35.3 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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