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Series GSE68031 Query DataSets for GSE68031
Status Public on Sep 20, 2020
Title miRNA transcriptome profiling of spheroid-enriched cells with cancer stem cell properties in human breast MCF-7 cell line.
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Intro: Spheroid culture especially on MCF-7 cell has been used as in vitro CSC model for anti-CSC drug discovery.
Methods: Tumour spheroid of MCF-7 was generated and characterised for the biological features and CSCs characteristic comparing to the monolayer parental MCF-7 cells. Differential expression of miRNA between the spheroid and parental cells was evaluated using miRNA microarray expressions.
Overall design miRNA expression profiles of MCF-7 enriched CSCs spheroids and monolayer cultures were generated in triplicates by Affymetrix GeneChip miRNA_4.0 array.
Contributor(s) Boo L, Ho WY, Ali NM, Yeap SK, Ky H, Chan KG, Yin WF, Satharasinghe DA, Liew WC, Tan SW, Ong HK, Cheong SK
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Submission date Apr 20, 2015
Last update date Sep 22, 2020
Contact name norlaily mohd ali
Organization name Universiti Tunku Abdul Rahman
Department Faculty of Medicine and Health Sciences
Street address Universiti Tunku Abdul Rahman, Jln Sg Long
City Cheras
State/province Selangor
ZIP/Postal code 43000
Country Malaysia
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (6)
GSM1661397 MCF7_P_1
GSM1661398 MCF7_P_2
GSM1661399 MCF7_P_3
BioProject PRJNA281587

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68031_RAW.tar 4.9 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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