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Series GSE68028 Query DataSets for GSE68028
Status Public on Apr 20, 2015
Title The alteration of DNA methylation driven by HIV infection based on a pair of monozygotic twins (MeDIP-chip)
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary In this study, we have investigated the relationship between genome-wide DNA methylation pattern and HIV infection using the methylated DNA immunoprecipitation - microarray method. A pair of monozygotic twins was recruited: one of the twins was infected with HIV while the other was not.
The immunoprecipitated CpG-methylated DNA from HIV positive subject (test) and from HIV negative subject (input control) were labelled with Cy5 and Cy3 respectively
Overall design The methylated genomic DNA fragments from HIV+ and HIV- twins were hybridized on the same chip since the identical genetic background
Contributor(s) Zhang Y, Tsui S
Citation(s) 26039376, 26697319
Submission date Apr 20, 2015
Last update date Dec 24, 2015
Contact name Yinfeng Zhang
Organization name The Chinese University of Hong Kong
Street address 1 shatin road
City Hong Kong
ZIP/Postal code 0000
Country Hong Kong
Platforms (1)
GPL16284 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
Samples (1)
GSM1661380 PBMC-HIV_infection
BioProject PRJNA281583

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68028_RAW.tar 261.9 Mb (http)(custom) TAR (of PAIR)
Processed data included within Sample table

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