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Series GSE6802 Query DataSets for GSE6802
Status Public on Feb 27, 2007
Title Gene expression analysis of bronchial epithelial cells stimulated by different airway pathogens.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Bronchial epithelial cells represent the first line of defense against invading airborne pathogens. They are important contributors to innate mucosal immunity and provide a variety of anti-microbial effectors. To investigate the role of epithelial cells upon infection of airway pathogens, we stimulated BEAS-2B cells for 4 h with UV-inactivated bronchial pathogens including Staphylococcus aureus, Pseudomonas aeruginosa and Respiratory Syncitial Virus (RSV) that among other receptors can strongly activate TLR2, TLR4 and TLR3, respectively.
Keywords: expression profiling, response to pathogens
Overall design All conditions were done in triplicates except for Staphylococcus aureus, were two replicates were done. As a control, unstimulated BEAS-2B were used. Altogether 11 arrays were hybridized.
Contributor(s) Mayer AK, Muehmer M, Mages J, Gueinzius K, Hess C, Heeg K, Bals R, Lang R, Dalpke AH
Citation(s) 17312161
Submission date Jan 19, 2007
Last update date Dec 06, 2018
Contact name Joerg Mages
Organization name Technical University Munich
Department Institute of Medical Microbiology, Immunology and Hygiene
Street address Trogerstrasse 30
City Munich
ZIP/Postal code 81675
Country Germany
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (11)
GSM157034 control_rep1
GSM157035 control_rep2
GSM157036 control_rep3
BioProject PRJNA99201

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Supplementary file Size Download File type/resource
GSE6802_RAW.tar 21.9 Mb (http)(custom) TAR (of CEL)

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