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Series GSE66719 Query DataSets for GSE66719
Status Public on Mar 11, 2015
Title SF3B1 Degron knockdown RNA-seq
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Knockdown of mutant and/or wild-type SF3B1 in MEL202 cell line by Degron knock-in, followed by RNA-seq, to identify splicing events governed by mutant SF3B1.
Overall design Control: parental MEL202 cell line. Experiments: mutant-SF3B1 knockdown; wildtype-SF3B1 knockdown; mutant SF3B1 knockout. Treatments: each of these four conditions plus and minus shld.
Contributor(s) Derti A, Zhou Q, Stegmeier F, Ruddy D
Citation(s) 25788694
Submission date Mar 10, 2015
Last update date May 15, 2019
Contact name Adnan Derti
Organization name personal
Department Bioinformatics
Street address 100 Alden Street
City Dedham
State/province MA
ZIP/Postal code 02026
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (8)
GSM1630516 Mel202 parental cells repeat #1 plus Shld
GSM1630517 Mel202 parental cells repeat #1 minus Shld
GSM1630518 Mel202 mut-SF3B1 KO plus Shld (2 days)
BioProject PRJNA277802
SRA SRP056033

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Supplementary file Size Download File type/resource
GSE66719_gene.expression.rescaled.75.10.txt.gz 1.5 Mb (ftp)(http) TXT
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Processed data are available on Series record
Raw data are available in SRA

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