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Series GSE66551 Query DataSets for GSE66551
Status Public on Mar 06, 2015
Title Nuclear orphan receptor TLX affects gene expression in pancreatic beta cells
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Using Illumina’s digital gene expression (DGE) system, we investigated the transcriptional response to TLX overexpression in beta cells. Finally, an average of 13,791,918 and 12,476,623 reads of high quality clean tags were obtained from control and TLX-overexpressing beta cells, respectively. Results reveals that overexpression of TLX resulted in suppression of 176 genes by ≥50%, and also results in ≥2-fold upregulation of 49 genes.
Overall design Expression profiling of stable TLX overexpressing MIN6 cells and control cells by high throughput sequencing
Contributor(s) Shi X, Xu Y
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Submission date Mar 05, 2015
Last update date May 15, 2019
Contact name XiaoLi Shi
Organization name WuHan University
Street address DongHU road
City WuHan
ZIP/Postal code 430071
Country China
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (4)
GSM1624826 s1a
GSM1624827 s2a
GSM1624828 s1b
BioProject PRJNA277312
SRA SRP055859

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE66551_gene.count.txt.gz 514.0 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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