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Series GSE66403 Query DataSets for GSE66403
Status Public on Sep 01, 2016
Title cGMP inducer effect on cell line Panc-1
Organism Homo sapiens
Experiment type Expression profiling by array
Summary cGMP is well-known secound messanger involved in vascular homeostasis. However little is known the effect of cGMP inducer on mRNA expression in cancer cells.
We performed microarrays to revealed the transcriptional change of a human pancreatic ductal adenocarcinoma (PDCA) cell line (Panc -1) to cGMP inducer Bay41-2272 in order to provide insight into impact of cGMP induction on Panc-1 cells.
 
Overall design Panc-1 Human PDCA cells were treated with vehicle (DMSO) or 5 μM Bay41-2272 for 48 h and total RNA was extracted by using TRIzol Reagent. The microarray analysis was conducted on the Panc-1 cells expressing by using Agilent Microarray.
 
Contributor(s) Kumazoe M, Takai M, Tachibana H
Citation(s) 28507102
Submission date Mar 02, 2015
Last update date Aug 28, 2019
Contact name Motofumi Kumazoe
E-mail(s) obc2509jmk@yahoo.co.jp
Organization name Faculty of Agriculture, Kyushu University, Fukuoka
Department Department of Bioscience and Biotechnology
Lab Laboratory of Food Chemistry, Division of Applied Biological Chemistry
Street address 6-10-1 Hakozaki, Higashi-ku
City Fukuoka
State/province Fukuoka
ZIP/Postal code 812-8581
Country Japan
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (2)
GSM1621543 Panc-1_48 hr_DMSO
GSM1621544 Panc-1_48 hr_Bay41-2272
Relations
BioProject PRJNA276795

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE66403_RAW.tar 24.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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