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Series GSE6596 Query DataSets for GSE6596
Status Public on Jan 12, 2007
Title Comparison of gene expression data from human and mouse breast cancers: Identification of conserved breast tumor genes
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The aim of our work was the comparison of human and mouse gene expression data and to identify a conserved breast tumor gene set. The results encourage the usefulness of transgenic mice as a model for human breast cancer formation and therapy.
Keywords: Comparison of gene expression data
Overall design The aim of our work was to establish a database for breast cancer gene expression data in order to compare human and mouse breast cancer. We identified human and mouse homologues genes and compared the expression profile of 24 human breast tumors with six WAP-SVT/t breast tumors (WAP-SVT/t animals, line 8). Our studies confirmed the heterogeneity in gene expression of human as well as mouse breast cancer cells. However, 63 genes were found to be differentially expressed (upregulated: 40; downregulated: 23 genes) in at least 75% of the breast tumors of both species.
Web link
Contributor(s) Seitz S, Klein A, Schmutzler R, Niederacher D, Arnold N, Meindl A, Scherneck S, Graessmann A
Citation(s) 17410534
Submission date Dec 21, 2006
Last update date Aug 10, 2018
Contact name Andreas Klein
Phone +49 30 450 528087
Fax +49 30 450 52945
Organization name Charité (CCO)
Department Institute of Biochemistry
Street address Charitéplatz 1
City Berlin
ZIP/Postal code 10117
Country Germany
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (26)
GSM152336 692N
GSM152337 Npool
GSM152338 01T
This SubSeries is part of SuperSeries:
GSE6772 Comparison of gene expression data from human and mouse breast cancers
BioProject PRJNA104185

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE6596_RAW.tar 94.4 Mb (http)(custom) TAR (of CEL)

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