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Series GSE65694 Query DataSets for GSE65694
Status Public on Feb 07, 2015
Title MicroRNA profiling in HEK293T cells after NDV infection
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Mammals have highly evolved receptors for sensing invading viral pathogens. RLRs comprise of one such family of receptors involved in sensing RNA viruses. The antiviral signaling cascade is tightly regulatedd by various post transcriptional modifications however the post transcriptional regulation by microRNAs is not well understood. We performed miRNA profiling to identify miRNAs induced by virus infections with potential role in regulating RLR signaling cascade.
Overall design We infected HEK293T cells with NDV-LasoTa strain for 6h. Total small RNA was isolated and hybridised on the Affymetrix miRNA Gene Chip 4.0. We sought to identify novel miRNAs targeting the antiviral signaling.
Contributor(s) Ingle H, Kumar S, Raut AA, Mishra A, Kameyama T, Takaoka A, Akira S, Kumar H
Citation(s) 26645583
Submission date Feb 06, 2015
Last update date May 02, 2017
Contact name Himanshu Kumar
Organization name IISER Bhopal
Department Biological Sciences
Lab 215
Street address Indore bypass road
City Bhopal
State/province MADHYA PRADESH
ZIP/Postal code 462066
Country India
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (4)
GSM1603264 Uninfected-Rep1
GSM1603265 Uninfected-Rep2
GSM1603266 NDV-6h-Rep1
BioProject PRJNA274735

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE65694_RAW.tar 3.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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