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Series GSE64934 Query DataSets for GSE64934
Status Public on Jul 03, 2015
Title Chronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific chromatin signature [Methylation]
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary We performed genome-wide DNaseI hypersensitive site in FLT3-ITD and WT patient samples. We report corresponding gene expression, promoter methylation patterns of differential DHSs as well as differentially occupied TF binding motifs using surrounding DNAseI cut profiles. We examined association patterns of FLT3 ITD and WT AMLs and found that FLT3-ITD signaling is associated with common gene expression and chromatin signature.
 
Overall design Examination of DNA methylation patterns in FLT3 ITD and WT AML via microarray study.
 
Contributor(s) Cauchy P, James S, Ptasinska A, Zacarias-Cabeza J, Imperato MR, Assi S, Piper J, Ott S, Bonifer C, Cockerill P
Citation(s) 26212328
Submission date Jan 13, 2015
Last update date Mar 22, 2019
Contact name Pierre Daniel Cauchy
E-mail(s) cauchy@ie-freiburg.mpg.de
Phone +49 (0)761 5108-730
Organization name Max Planck Institute of Immunobiology and Epigenetics
Department Department of Cellular and Molecular Immunology
Lab Laboratory Rudolf Grosschedl
Street address St├╝beweg 51
City Freiburg
State/province Baden-W├╝rttemberg
ZIP/Postal code 79108
Country Germany
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (9)
GSM1584041 CD14
GSM1584042 CD34
GSM1584043 ITD1
This SubSeries is part of SuperSeries:
GSE64874 Chronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific chromatin signature
Relations
BioProject PRJNA272531

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64934_RAW.tar 183.1 Mb (http)(custom) TAR
GSE64934_TPS1928_GroupMethylationProfile_FinalReport_20Jun11_AML.txt.gz 154.4 Mb (ftp)(http) TXT
GSE64934_unmethylated_methylated.txt.gz 22.2 Mb (ftp)(http) TXT
Processed data included within Sample table

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