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Series GSE64873 Query DataSets for GSE64873
Status Public on Jul 03, 2015
Title Chronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific chromatin signature [Agilent]
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We performed genome-wide DNaseI hypersensitive site in FLT3-ITD and WT patient samples. We report corresponding gene expression, promoter methylation patterns of differential DHSs as well as differentially occupied TF binding motifs using surrounding DNAseI cut profiles. We examined association patterns of FLT3 ITD and WT AMLs and found that FLT3-ITD signaling is associated with common gene expression and chromatin signature.
 
Overall design Examination of gene expression patterns in FLT3 ITD and WT AML via microarray study.
 
Contributor(s) Cauchy P, James S, Ptasinska A, Zacarias-Cabeza J, Imperato MR, Assi S, Piper J, Ott S, Bonifer C, Cockerill P
Citation(s) 26212328
Submission date Jan 12, 2015
Last update date Nov 27, 2018
Contact name Pierre Daniel Cauchy
E-mail(s) cauchy@ie-freiburg.mpg.de
Phone +49 (0)761 5108-730
Organization name Max Planck Institute of Immunobiology and Epigenetics
Department Department of Cellular and Molecular Immunology
Lab Laboratory Rudolf Grosschedl
Street address St├╝beweg 51
City Freiburg
State/province Baden-W├╝rttemberg
ZIP/Postal code 79108
Country Germany
 
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (23)
GSM1581904 normal_CD14_BM
GSM1581905 Ewing_PBSC_1
GSM1581906 Ewing_PBSC_2
This SubSeries is part of SuperSeries:
GSE64874 Chronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific chromatin signature
Relations
BioProject PRJNA272429

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64873_RAW.tar 76.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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