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Series GSE64510 Query DataSets for GSE64510
Status Public on Jun 01, 2015
Title Analysis of Nestin-GFP+ pericytes from adipose tissue: PDGFRa wild type versus PDGFRa+/D842V (constitutively active mutant)
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Analysis of Nestin-GFP+ pericytes flow sorted from 3-day-old mouse cutaneous adipose tissue, comparing controls with wild type PDGFRa, and mutants with increased PDGFRa signaling driven by a Cre/lox-inducible D842V knockin mutation in the PDGFRa kinase domain. The control cells have adipogenic properties in vitro or when transplanted subcutaneously into recipient mice. The D842V mutant cells show altered behavior in the same assays, with poor adipogenic differentiation but a propensity to transition into profibrotic cells that secrete collagen
 
Overall design 3 Nes-GFP+ cells samples; 3 Nes-GFP;Nes-Cre;PDGFRα+/[S]D842V samples
 
Contributor(s) Olson LE, Iwayama T
Citation(s) 26019175
Submission date Dec 24, 2014
Last update date May 15, 2019
Contact name Mikhail Dozmorov
E-mail(s) mdozmorov@vcu.edu
Organization name Virginia Commonwealth University
Department Biostatistics
Street address 830 E Main St
City Richmond
State/province VA
ZIP/Postal code 23298
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (6)
GSM1573101 Nes-GFP+ cells 1
GSM1573102 Nes-GFP+ cells 2
GSM1573103 Nes-GFP+ cells 3
Relations
BioProject PRJNA271156
SRA SRP051537

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64510_RAW.tar 860.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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