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Series GSE64490 Query DataSets for GSE64490
Status Public on Jun 03, 2015
Title DNA methylation profiles of human bone samples
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary The main goal of the study was to measure the epigenetic age (also known as DNA methylation age) of human bone tissue and to relate it to chronological age. Toward this end, we used the epigenetic clock software described in Horvath S (2013) DNA methylation age of human tissues and cell types. Genome Biology.2013, 14:R115. DOI: 10.1186/10.1186/gb-2013-14-10-r115 PMID: 24138928
 
Overall design Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 486,000 CpGs. The trabecular bone pieces were obtained from the central part of the femoral head of Spanish (Caucasian) patients with hip fractures (due to osteoporosis) or subjects with osteoarthritis. About 85% of the cell population in this bone tissue are osteocytes and the remainder are osteoblasts, bone marrow, etc.
 
Contributor(s) Horvath S, Riancho Moral JA
Citation(s) 26000617
Submission date Dec 23, 2014
Last update date Mar 22, 2019
Contact name Steve Horvath
E-mail(s) shorvath@altoslabs.com
Organization name University of California, Los Angeles
Department Human Genetics
Lab Horvath
Street address 695 Charles E. Young Drive South, Box 708822
City Los Angeles
State/province CA
ZIP/Postal code 90095-7088
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (48)
GSM1572334 genomic DNA from bone of subject 1
GSM1572335 genomic DNA from bone of subject 2
GSM1572336 genomic DNA from bone of subject 3
This SubSeries is part of SuperSeries:
GSE64511 DNA methylation profiles of multiple human tissues
Relations
BioProject PRJNA271163

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64490_Explanation_of_characteristic_variables2_bone.txt.gz 471 b (ftp)(http) TXT
GSE64490_RAW.tar 183.1 Mb (http)(custom) TAR
GSE64490_datSignal_bone.csv.gz 114.9 Mb (ftp)(http) CSV
Processed data included within Sample table
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