|
| Status |
Public on Dec 09, 2015 |
| Title |
Dynamic interplay between the transcriptome and methylome in response to oxidative and alkylating stress |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
Methyl radicals are not able to form 5'methylcytosine directly. However, tert-butylhydroperoxide-induced responses in the transcriptome are partly regulated by the methylome to restore normal cellular function
|
| |
|
| Overall design |
Cells were exposed to tert-butylhydroperoxide (TBH, Sigma) at a concentrations of 200 µM for 1, 8 and 24 hours
|
| |
|
| Contributor(s) |
Deferme L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 09, 2014 |
| Last update date |
Dec 10, 2015 |
| Contact name |
Lize Deferme |
| E-mail(s) |
l.deferme@maastrichtuniversity.nl
|
| Organization name |
Maastricht University
|
| Department |
TGX
|
| Street address |
Universiteitssingel 50
|
| City |
Maastricht |
| State/province |
Limburg |
| ZIP/Postal code |
6200MD |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL16284 |
NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1] |
|
| Samples (18)
|
|
| Relations |
| BioProject |
PRJNA269728 |
Less...
More...