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Series GSE63938 Query DataSets for GSE63938
Status Public on Dec 01, 2017
Title Targeted CpG island methylation in human pluripotent stem cells
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary In our manuscript, we describe novel methodologies for bidirectional DNA methylation editing at targeted genomic loci through homologous recombination (HR) in human pluripotent stem cells. In order to gain insights on the applicability of these methodologies towards modeling epigenetic alterations, as well as for the development of platforms for cell transplantation upon epigenetic correction.
Overall design Analysis of targeted CpG island methylation
Contributor(s) Takahashi Y, Shokhirev MN, Benner C
Citation(s) 28473583
Submission date Dec 08, 2014
Last update date Mar 28, 2022
Contact name April Elizabeth Williams
Phone 7345461645
Organization name Salk Institute for Biological Studies
Department IGC
Street address 10010 N Torrey Pines Rd
City San Diego
State/province California
ZIP/Postal code 92037
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (29)
GSM1560892 WT iPS
GSM1560893 AS iPS
GSM1560894 HR AS iPS 9
BioProject PRJNA269567
SRA SRP050889

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE63938_MLH1andSNRPN.fa.gz 2.8 Kb (ftp)(http) FA
GSE63938_RAW.tar 1.8 Gb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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