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Series GSE63813 Query DataSets for GSE63813
Status Public on Feb 02, 2015
Title RNA sequencing of allelic series of miR-17~92 mutant embryos.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We report the generation of an allelic series of miR-17~92 mutant mice, each carrying the targeted deletion of specific miRNA families encoded by the cluster. We integrate the phenotypic characterization of these strains with RNA-seq analysis showing the consequences of selective miRNA inactivation on gene expression in the developing embryo.
Overall design We generated and analyzed RNA-seq data from 8 different miR-17~92 alleles, in three different microdissected tissues collected from E9.5 mouse embryos. Datasets contain biological triplicates (except for duplicates in one case, Delta_17_18_92) for a total of 71 samples.
Contributor(s) Betel D, Han Y, Vidigal JA, Singh I, Gonzalez A, Leslie C, Ventura A
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Submission date Dec 03, 2014
Last update date May 15, 2019
Contact name Andrea Ventura
Phone 6468883068
Organization name Memorial Sloan Kettering Cancer Center
Department Cancer Biology & Genetics Program
Lab Ventura
Street address 408 East 69th, ZRC-1201
City New York
State/province NY
ZIP/Postal code 10065
Country USA
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (71)
GSM1557957 Wild-type_TB_1
GSM1557958 Wild-type_TB_2
GSM1557959 Wild-type_TB_3
BioProject PRJNA269137
SRA SRP050491

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE63813_countTable.txt.gz 2.5 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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