GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE63695 Query DataSets for GSE63695
Status Public on Sep 02, 2015
Title Characterization of the cartilage DNA methylome in knee and hip osteoarthritis.
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary The aim of this study was to characterise the genome-wide DNA methylation profile of osteoathritis (OA) chondrocytes from both knee and hip cartilage, providing the first comparison of DNA methylation between OA and non-OA hip cartilage, and between OA hip and OA knee cartilage. The study was performed using the Illumina Infinium HumanMethylation450 BeadChip array. Genome-wide methylation was assesed in chondrocyte DNA extracted from 23 OA hip, 73 OA knee and 21 healthy hip controls (NOF - neck of femure samples).

Keywords: Methylation profiling by array
Overall design Bisulphite converted DNA from the 97 samples were hybridised to the Illumina Infinium HumanMethylation450 BeadChip array.
Contributor(s) Skelton AJ, Reynard LN, Loughlin J, Rushton MD
Citation(s) 24838673
Submission date Sep 01, 2015
Last update date Mar 22, 2019
Contact name Andrew James Skelton
Organization name Newcastle University
Department Bioinformatics
Lab Musculoskeletal Research Group
Street address Framlington Place
City Newcastle upon Tyne
State/province Tyne and Wear
ZIP/Postal code NE2 4HH
Country United Kingdom
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (97)
GSM1867741 Hip_Control 1
GSM1867742 Hip_Control 2
GSM1867743 Hip_Control 3
BioProject PRJNA294636

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE63695_RAW.tar 970.0 Mb (http)(custom) TAR (of IDAT)
GSE63695_unmethylated_methylated.txt.gz 250.8 Mb (ftp)(http) TXT
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap