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Series GSE63409 Query DataSets for GSE63409
Status Public on Oct 01, 2015
Title Epigenome analysis of leukemia stem, blast and normal hematopoietic stem/progenitor cells
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Genome wide DNA methylation profiling of leukemia stem, blast cells obtained from 15 AML patients and of normal hematopoietic stem/progenitor cells from 5 normal bone marrow. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in the samples. Samples included 20 leukemia stem cells, 24 blast cells and 30 normal hematopoietic stem and progenitor cells (6 different types from 5 normal bone marrows).
 
Overall design Bisulphite converted DNA from the 74 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip
 
Contributor(s) Jung N
Citation(s) 26444494
Submission date Nov 18, 2014
Last update date Jul 13, 2023
Contact name Andrew Feinberg
Organization name Johns Hopkins University
Department Medicine
Lab Center for Epigenetics
Street address 855 N. Wolfe St., Rangos 570
City Baltimore
State/province MD
ZIP/Postal code 21205
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (74)
GSM1548150 genomic DNA from HSC of normal bone marrow ID2748
GSM1548151 genomic DNA from MPP of normal bone marrow ID2748
GSM1548152 genomic DNA from L-MPP of normal bone marrow ID2748
Relations
BioProject PRJNA267692

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE63409_RAW.tar 791.2 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table
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