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Series GSE62878 Query DataSets for GSE62878
Status Public on Jul 10, 2015
Title Expression profiles of liver tissues from wild-type and AID transgenic mice exposed to thioacetamide hepatotoxicity
Organism Mus musculus
Experiment type Expression profiling by array
Summary AID is an intrinsic DNA mutator enzyme and contributes to tumorigenesis through the accumulation of genetic aberrations. To examine whether mutagenesis induced by AID during inflammation-associated hepatocarcinogenesis depends on the transcriptional levels of the target genes, we performed the gene expression profiling of liver tissues from AID transgenic mice and wild-type mice with and without thioacetamide treatment.
Overall design AID transgenic mice and wild-type mice were administered with thioacetamide in drinking water for 6 months, and the gene expression levels of their livers are compared.
Contributor(s) Matsumoto T, Marusawa H
Citation(s) 25969143
Submission date Oct 30, 2014
Last update date Jan 19, 2018
Contact name Tomonori Matsumoto
Organization name Osaka University
Street address 3-1 Yamadaoka
City Suita
State/province Osaka
ZIP/Postal code 565-0871
Country Japan
Platforms (1)
GPL10333 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version)
Samples (2)
GSM1535473 thioacetamide treatment effect on wild-type mouse liver
GSM1535474 thioacetamide treatment effect on AID transgenic mouse liver
BioProject PRJNA265874

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE62878_RAW.tar 37.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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