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| Status |
Public on Dec 30, 2018 |
| Title |
Whole genome expression in peripheral whole blood of chronic kidney disease patients having uncertain etiology (CKDu) compared to healthy controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Chronic kidney disease of uncertain etiology (CKDu) is an increasing problem in Sri Lanka especially among the farming community. The etiologies although uncertain, have been associated with occupational and environmental factors. The expression pattern of genes in blood of these CKDu patients in an endemic region of Sri Lanka was analyzed compared to healthy individuals from a non-endemic region to see any expression changes that could be associated to environmental factors. Pattern of expression changes could lead to either strengthen or weaken current hypotheses for the causes.
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| Overall design |
RNA extracted from blood of CKDu patients from a CKDu-endemic area were pooled stage-wise. Pooled RNA extracted from blood of healthy individuals of an area not endemic to CKDu were used as controls. Three technical replicates were performed for each of the pooled samples.
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| Contributor(s) |
Sayanthooran S, Magana-Arachchi DN, Gunerathne L |
| Citation(s) |
29808448 |
| |
| Submission date |
Oct 29, 2014 |
| Last update date |
Dec 30, 2018 |
| Contact name |
Dhammika Magana-Arachchi |
| E-mail(s) |
dmaganaarachchi@gmail.com
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| Organization name |
National Institute of Fundamental Studies
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| Department |
Cell Biology
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| Lab |
Cell Biology
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| Street address |
Hantana Road
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| City |
Kandy |
| State/province |
Central |
| ZIP/Postal code |
20000 |
| Country |
Sri Lanka |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA265159 |
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