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Series GSE62585 Query DataSets for GSE62585
Status Public on Dec 31, 2016
Title Development of NUP98-HOXA9 gene expression signatures
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To explore the molecular mechanisms induced by the leukemic fusion protein NUP98-HOXA9, we performed gene expression analysis of human hematopoietic progenitors and primary samples of patients that express NUP98-HOXA9. By combining these data with ChIP-seq results, we observed that the fusion protein is able to both activate and repress the expression of its target genes.
 
Overall design Three independent experiments were performed using different clones of the human hematopoietic progenitor model (hHP-NH) and control model (hHP-empty vector). On the other hand, RNA from seven primary samples was analyzed.
 
Contributor(s) Rio-Machin A, Cigudosa CJ
Citation(s) 28630438
Submission date Oct 22, 2014
Last update date Jun 26, 2019
Contact name Ana Del Rio
E-mail(s) adelrio@cnio.es
Organization name CNIO
Street address Calle Melchor Fernandez Almagro 3
City Madrid
State/province Madrid
ZIP/Postal code 28029
Country Spain
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (9)
GSM1529664 hHP-NUP98-HOXA9 clone 1
GSM1529665 hHP-NUP98-HOXA9 clone 2
GSM1529666 Patient 1
This SubSeries is part of SuperSeries:
GSE62587 NUP98-HOXA9 role as oncogenic transcription factor
Relations
BioProject PRJNA264479

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE62585_RAW.tar 27.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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