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Series GSE6253 Query DataSets for GSE6253
Status Public on Nov 10, 2006
Title A Gene Expression Signature Predicts Survival of Patients with Stage I Non-Small Cell Lung Cancer
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We applied a meta-analysis of datasets from seven different microarray studies on lung cancer for differentially expressed genes related to survival time (under 2 y and over 5 y). Systematic bias adjustment in the datasets was performed by distance-weighted discrimination (DWD). We identified a gene expression signature consisting of 64 genes that is highly predictive of which stage I lung cancer patients may benefit from more aggressive therapy.
Keywords: disease state analysis
Overall design RNA was extracted from frozen tissue of primary stage I Non-Small Cell lung tumors for gene array analysis
Contributor(s) Lu Y, You M, Watson M, Govindan R, Sun Z, Yang P
Citation(s) 17194181
Submission date Nov 08, 2006
Last update date Dec 13, 2018
Contact name Yan Lu
Organization name washington univ.
Street address 660 s. euclid ave
City st louis
State/province MO
ZIP/Postal code 63110
Country USA
Platforms (3)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
GPL97 [HG-U133B] Affymetrix Human Genome U133B Array
GPL8300 [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Samples (72)
GSM143929 Adenocarcinoma 3196
GSM143930 Adenocarcinoma 3197
GSM143931 Squamous cell carcinoma 3198
BioProject PRJNA99683

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Supplementary file Size Download File type/resource
GSE6253_RAW.tar 219.8 Mb (http)(custom) TAR (of CEL)

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