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| Status |
Public on Oct 07, 2014 |
| Title |
CD161 defines a transcriptional and functional phenotype shared across distinct human T cell lineages (CD4) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
T lymphocytes are conventionally divided into subsets based upon expression of co-receptors, cytokines and surface molecules. By mRNA microarray analysis, T lymphocytes that express the C-type lectin CD161 were identified to share a transcriptional profile, which led to the identification of an innate function across these previously defined subsets, including CD8, CD4 and TCRgd T cells.
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| Overall design |
Gene expression of magnetically enriched, resting CD161+ and CD161- CD4+ T cells from peripheral blood was measured in 3 healthy donors.
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| Contributor(s) |
Fergusson JR, Fleming V, Lockstone H, Marchi E, Klenerman P |
| Citation(s) |
25437561, 29423939 |
| Submission date |
Oct 06, 2014 |
| Last update date |
May 17, 2019 |
| Contact name |
Joannah R Fergusson |
| Organization name |
University of Oxford
|
| Department |
Peter Medawar Building for Pathogen Research
|
| Street address |
South Parks Road
|
| City |
Oxford |
| State/province |
select a state |
| ZIP/Postal code |
OX1 3SY |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE62099 |
CD161 defines a transcriptional and functional phenotype shared across distinct human T cell lineages |
|
| Relations |
| BioProject |
PRJNA263190 |
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