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| Status |
Public on Aug 27, 2015 |
| Title |
Low dose of DNA-demethylating agents target colorectal cancer-initiating cells by activation of RIG1/MAVS signaling pathway |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
Genome wide DNA methylation profiling of 3 patient-derived colorectal cancer samples with different CIMP profiles. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs
|
| |
|
| Overall design |
Bisulphite converted DNA from the 3 samples were hybridised to the Illumina HumanMethylation450 BeadChip
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| |
|
| Contributor(s) |
De Carvalho D, Singhania R |
| Citation(s) |
26317465 |
| Submission date |
Oct 06, 2014 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Daniel De Carvalho |
| E-mail(s) |
ddecarv@uhnresearch.ca
|
| Organization name |
Princess Margaret Cancer Centre
|
| Street address |
101 College St
|
| City |
Toronto |
| State/province |
ON |
| ZIP/Postal code |
M5G 1L7 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
|
| Samples (3) |
| GSM1519484 |
genomic DNA from colorectal cancer sample #73 (non-CIMP) |
| GSM1519485 |
genomic DNA from colorectal cancer sample #92 (CIMP high) |
| GSM1519486 |
genomic DNA from colorectal cancer sample #181 (CIMP low) |
|
| Relations |
| BioProject |
PRJNA263174 |
