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Series GSE62053 Query DataSets for GSE62053
Status Public on Mar 01, 2015
Title S-adenosylmethionine (SAM) changes DNA methylation patterns in prostate cancer cells
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome-wide DNA methylation profiling of human PC3 invasive prostate cancer cell line treated with vehicle control (SAH, S-adenosylhomocysteine) and with SAM (S-adenosylmethionine) as well as of untreated human LNCaP non-invasive prostate cancer cell line. The Illumina Infinium 450k Human DNA Methylation BeadChip v1.2 was used to obtain DNA methylation profiles across approximately 450,000 CpGs in human cell lines exposed to described treatments. Samples included biological triplicate of PC3 control (SAH treated), biological triplicate of PC3 treated with SAM, and biological duplicate of LNCaP untreated.
Overall design Bisulfite-converted DNA from the 8 samples were hybridised to the Illumina Infinium 450k Human Methylation BeadChip v1.2.
Contributor(s) Shukeir N, Stefanska B, Parashar S, Chik F, Arakelian A, Szyf M, Rabbani SA
Citation(s) 25631332
Submission date Oct 03, 2014
Last update date Mar 22, 2019
Contact name Barbara Stefanska
Organization name The University of British Columbia
Department Land and Food Systems
Lab Stefanska Lab
Street address 2205 East Mall
City Vancouver
State/province BC
ZIP/Postal code V6T 1Z4
Country Canada
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (8)
GSM1519011 PC3 cells treated with vehicle control (SAH), biological replicate 1
GSM1519012 PC3 cells treated with vehicle control (SAH), biological replicate 2
GSM1519013 PC3 cells treated with vehicle control (SAH), biological replicate 3
BioProject PRJNA263087

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Supplementary file Size Download File type/resource
GSE62053_RAW.tar 249.4 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

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