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Series GSE61428 Query DataSets for GSE61428
Status Public on Feb 12, 2015
Title Cohesin regulates gene expression through spatial clustering of enhancer elements
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary H3K27Ac ChIP-seq in wild type and cohesin-deficient thymocytes
Overall design Rad21 was deleted in CD4+ CD8+ double positive (DP) thymocytes by crossing a Rad21 floxed allele with a Cd4-driven Cre transgene. DP positive thymocytes were FACS-sorted from control and Rad21-/- littermates, which were then used to perform chromatin immunoprecipitation for histone H3 acetylated on lysine 27 (H3K27Ac).
Contributor(s) Merkenschlager M
Citation(s) 25677180
Submission date Sep 15, 2014
Last update date May 15, 2019
Contact name Gopuraja Dharmalingam
Organization name MRC London Institute of Medical Sciences
Department Epigenetics section
Street address Faculty of Medicine, Imperial College, Hammersmith Hospital Campus
City London
ZIP/Postal code W12 0NN
Country United Kingdom
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (11)
GSM1504380 Input WT 1
GSM1504381 Input WT 2
GSM1504382 Input KO 1
BioProject PRJNA261059
SRA SRP047133

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE61428_RAW.tar 3.9 Gb (http)(custom) TAR (of BED, WIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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