GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE61177 Query DataSets for GSE61177
Status Public on Jul 01, 2015
Title Myocardial gene expression in response to pressure overload
Organism Mus musculus
Experiment type Expression profiling by array
Summary Myocardial deletion of klf4 sensitizes mouse to pressure overload. In order to gain a better understanding of molecular mechanisms of such alterations, we profiled gene expression before and after 3-day of pressure overload (induced by transverse aortic constriction -TAC) in the hearts from MHC-cre (Cre) control and MHC-cre-klf4-deficient (KO) mice.
Overall design 10wk old male mice was subjected to transverse aortic constriction (TAC) to induce pressure overload or sham operation as control group. After 3 days, heart was removed and total RNA was extracted from apex and subjected for array analysis. Four animals in each group.
Contributor(s) Liao X, Jain MK
Citation(s) 26241060
Submission date Sep 05, 2014
Last update date Jan 12, 2017
Contact name Mukesh Jain
Organization name Case Western Reserve University
Street address 2103 Cornell Rd
City Cleveland
State/province OH
ZIP/Postal code 44106
Country USA
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (15)
GSM1498924 heart-Cre.Control.763
GSM1498925 heart-Cre.Control.771
GSM1498926 heart-Cre.Control.881
BioProject PRJNA260410

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE61177_RAW.tar 33.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap