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Series GSE60683 Query DataSets for GSE60683
Status Public on Jun 12, 2017
Title LASSIM -a network inference toolbox for genome-wide mechanistic modeling
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We present LASSIM, which is a toolbox built to build and infer parameters within mechanistic models on a genomic scale. This is made possible due to a property shared across biological systems, namely the existence of a subset of master regulators, here denoted the core system. The introduction of a core system of genes simplifies the inference into small solvable sub-problems, and implies that all main regulatory actions on peripheral genes come from a small set of regulator genes. This separation allows substantial parts of computations to be solved in parallel, i.e. permitting the use of a computer cluster, which substantially reduces the time for the computation to finish.
Overall design Refer to individual Series
Contributor(s) Magnusson R, Mariotti GP, Köpsén M, Lövfors W, Gawel DR, Jörnsten R, Linde J, Nordling T, Nyman E, Schulze S, Nestor CE, Zhang H, Cedersund G, Benson M, Tjärnberg A, Gustafsson M
Citation(s) 28640810
Submission date Aug 22, 2014
Last update date Jan 23, 2019
Contact name Danuta Gawel
Organization name Linköping University
Street address Garnisonsvägen
City Linköping
ZIP/Postal code 58185
Country Sweden
Platforms (3)
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
GPL14550 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (70)
GSM1484768 0h of polarization 1
GSM1484769 0h of polarization 2
GSM1484770 6h of polarization 1
This SuperSeries is composed of the following SubSeries:
GSE60681 LASSIM -a network inference toolbox for genome-wide mechanistic modeling [Time-series polarization: CD4+ T cells toward Th2]
GSE65880 LASSIM -a network inference toolbox for genome-wide mechanistic modeling [MAF, MYB & GATA3 siRNA]
GSE95508 LASSIM -a network inference toolbox for genome-wide mechanistic modeling [USF2, KLF6/COPEB, CBL and HIS1 siRNA]]
BioProject PRJNA259237

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE60683_RAW.tar 201.2 Mb (http)(custom) TAR (of TXT)

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