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Series GSE59999 Query DataSets for GSE59999
Status Public on Jan 01, 2015
Title Blood DNA methylation biomarkers predict clinical reactivity in food-sensitized infants
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome wide DNA methylation profiling study of PBMC from 71 unique primary patient blood samples. The Illumina Human Methylation 450k array was used. 29 challenge proven food allergy, 29 sensitized but oral tolerant, 13 non food allergics
Mixture of food allergy phenotypes (egg allergic (15), peanut allergic (14)), food sensitization phenotypes (egg sensitized (14), peanut sensitized (15)). 4 samples had technical replicate hybridzations.
Overall design Bisulphite converted DNA from the 75 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip v1.2. Technical replicates were combined during processing, resulting in normalized Beta values for 71 unique primary patient blood samples.
Contributor(s) Martino DJ
Citation(s) 25678091
Submission date Aug 01, 2014
Last update date Mar 22, 2019
Contact name David Martino
Phone 0863191635
Organization name Telethon Kids Institute
Street address Perth Childrens Hospital, 15 Hospital Avenue
State/province Western Australia
ZIP/Postal code 6009
Country Australia
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (71)
GSM1463328 9020331094_R02C01
GSM1463329 9020331094_R03C01
GSM1463330 9020331094_R04C01
BioProject PRJNA257251

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59999_RAW.tar 183.1 Mb (http)(custom) TAR
GSE59999_signal_intensities.txt.gz 172.6 Mb (ftp)(http) TXT
Processed data included within Sample table

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