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Series GSE59902 Query DataSets for GSE59902
Status Public on Nov 30, 2014
Title DNA methylation study in breast cancer [aCGH]
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary Addressing the still unresolved question of the existence of CIMP in breast cancer DNA methylation alterations among histological breast cancer subtypes were examined by applying the HM450K BeadChip of Illumina Inc., covering about 480,000 single CpG sites. In addition to the occurrence of the hypermethylator phenotype in breast cancer, its relation to genetic instability and histological subtypes was investigated.
Overall design Bisulfite converted DNA from 32 fresh-frozen primary breast tissue samples and 4 breast cancer cell lines were hybridized onto the HumanMethylation 450K BeadChip from Illumina Inc. Additionally, 28 of these primary samples were analyzed by array-based comparative hybdridization (aCGH).
Contributor(s) Rößler J, Lehmann U, Ammerpohl O, Gutwein J, Steinemann D
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Submission date Jul 30, 2014
Last update date Nov 30, 2014
Contact name Jessica Rößler
Organization name Medical School Hannover
Department Pathology
Street address Carl-Neuberg Str. 1
City Hannover
ZIP/Postal code 30625
Country Germany
Platforms (1)
GPL10123 Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version)
Samples (28)
GSM1450472 TU_ILBC_1 [aCGH]
GSM1450473 TU_ILBC_2 [aCGH]
GSM1450474 TU_ILBC_3 [aCGH]
This SubSeries is part of SuperSeries:
GSE59903 DNA methylation study in breast cancer
BioProject PRJNA257040

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59902_RAW.tar 519.2 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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