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Series GSE59686 Query DataSets for GSE59686
Status Public on Nov 25, 2016
Title Gene profiling of the zone of altered morphology of choriodecidua overlying the cervix before labor in preterm samples
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To characterize the molecular signature of the choriodecidua remodeling in third trimestry of pregnancy before labour, we have employed whole genome microarray expression profiling. Fetal membranes were collected from women undergoing a emergency cesarean delivery before term (before 32 weeks of gestation and between 33-35 weeks of gestation), for preeclampsia and/or in utero growth retardation. During surgery, a Kocher's forceps was placed on membranes overlying the cervix and the area surrounding the forceps was dissected in the operating room under sterile conditions, the site, pinched by the forceps, being discarded. Fetal membranes in a remote zone were also sampled. Isolated RNAs were hybridized to the Aligent SurePrint G3 Human GE 8x60K Microarray.
Overall design Microarray analysis was conducted on four distincts groups overlying the cervix and remote from the cervix before 32 weeks of gestation (XPZ) or between 33 and 35 weeks of gestation (PZ) composed of three pools for the XPZ samples and two pools for the PZ samples, each pool consisted of three samples from three different women.
Contributor(s) Méhats C, Marcellin L, Jacques S
Citation(s) 28031337
Submission date Jul 23, 2014
Last update date Nov 27, 2018
Contact name Céline Méhats
Organization name Inserm
Department U1016
Street address 24 rue du Faubourg St jacques
City Paris
ZIP/Postal code 75014
Country France
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (10)
GSM1442856 XPZIM_replicate1
GSM1442857 XPZIM_replicate2
GSM1442858 XPZIM_replicate3
BioProject PRJNA255965

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59686_RAW.tar 54.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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