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Series GSE59250 Query DataSets for GSE59250
Status Public on Jul 10, 2014
Title DNA Methylation Analysis of Systemic Lupus Erythematosus
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary This study performed Illumina Methylation450 analysis of CD4+ T-cells, CD19+ B-cells and CD14+ Monocytes from lupus patients and controls. A validation cohort was further analyzed with the same platform using CD4+ T-cells, CD45RO-CD45RA+ naive T-cells, CD45RO+CD45RA- memory T-cells, and CD25+CD127- regulatory T-cells.
Overall design SLE v Control comparisions were made within each cell type. The SLE patient samples are labeled SLEnnnn and the controls Xnnnn. The cell type CD4, CD14, CD19, Tmem, Treg, Tnaive is appended to each sample ID.
Citation(s) 23950730
Submission date Jul 09, 2014
Last update date Mar 22, 2019
Contact name Devin Absher
Organization name HudsonAlpha Institute for Biotechnology
Street address 601 Genome Way
City Huntsville
State/province AL
ZIP/Postal code 35806
Country USA
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (434)
GSM1431412 X11560.CD14
GSM1431413 SLE3696.CD14
GSM1431414 SLE10347.CD14
BioProject PRJNA254821

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59250_RAW.tar 183.1 Mb (http)(custom) TAR
GSE59250_average_betas.txt.gz 826.7 Mb (ftp)(http) TXT
GSE59250_signal_intensities.txt.gz 966.8 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

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