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Series GSE58965 Query DataSets for GSE58965
Status Public on Mar 07, 2017
Title Identification of early and late responder genes during cell reprogramming of mouse fibroblasts into induced pluripotent stem cells
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Our recent approach to induction of pluripotent stem cells from fibroblasts using protein extract from mouse ESCs could overcome the potential tumorigenicity risks associated with random retroviral integration. Here we examine the epigenetic modifications and transcriptome in two kinds of iPSCs and a partially reprogrammed iPSC (iPSCp) generated from adult cardiac and skin fibroblasts independently to assess any perturbations of transcription program during reprogramming.
Overall design The histone H3K4me3 and H3K27me3 profiles were obtained from ESC, two kinds of iPSCs and a partially reprogrammed iPSC (iPSCp) generated from adult cardiac and skin fibroblasts.
Contributor(s) Park J, Kwon Y, Hong C, Seo S, Choe MK, Shin S, Paek JS, Kim H, Roh T
Citation(s) 28152015
Submission date Jul 01, 2014
Last update date May 15, 2019
Contact name Tae-Young Roh
Organization name Ewha Womans University
Department Life Sciences
Lab Sysgem Genomics
Street address 52 Ewhayeodae-gil, Seodaemun-gu
City Seoul
State/province --- Select One ---
ZIP/Postal code 03760
Country South Korea
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (14)
GSM1423139 cFB_H3K27me3
GSM1423140 cFB_H3K4me3
GSM1423141 iPSC1_H3K27me3
BioProject PRJNA254018
SRA SRP043695

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Supplementary file Size Download File type/resource
GSE58965_RAW.tar 202.5 Mb (http)(custom) TAR (of BEDGRAPH)
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Raw data are available in SRA
Processed data provided as supplementary file

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