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| Status |
Public on Jul 06, 2021 |
| Title |
Retinoblastoma gene expression data |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Retinoblastoma is the most common intraocular cancer of infancy and childhood, with an incidence of one case per 15,000 - 20,000 live births. An early event in retinoblastoma genesis is a functional loss of both alleles of the RB1 gene. However, other genes are likely to be involved in the development of this cancer. In this study we sought to build a comprehensive molecular portrait of this cancer by performing transcriptomic, methylomic, genomic profiling of primary retinoblastoma samples. Most of the patients whose tumors were studied had received no treatment prior to surgical enucleation.
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| Overall design |
Gene expression of 63 samples retinoblastomas tumor and 3 fetal retina were assesed using the Hg-U133 Plus 2.0 Affymetrix array
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| Contributor(s) |
Radvanyi F, Sefta M, Ottaviani D, Desbrousses C, Liu J, Chapeaublanc E |
| Citation(s) |
34552068 |
| |
| Submission date |
Jun 24, 2014 |
| Last update date |
Sep 24, 2021 |
| Contact name |
Elodie chapeaublanc |
| E-mail(s) |
elodie.chapeaublanc@pasteur.fr
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| Organization name |
Institut Curie
|
| Department |
UMR 144
|
| Lab |
Equipe Radvanyi
|
| Street address |
26 rue d'ulm
|
| City |
paris |
| ZIP/Postal code |
75248 |
| Country |
France |
| |
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| Platforms (1) |
| GPL28718 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray HGU133Plus2_Hs_ENTREZG_v23] |
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| Samples (66)
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| This SubSeries is part of SuperSeries: |
| GSE58785 |
Pan-genomic study of primary human retinoblastoma samples |
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| Relations |
| BioProject |
PRJNA253482 |
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