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Series GSE58617 Query DataSets for GSE58617
Status Public on Sep 10, 2015
Title ChIP-seq assays for H3K9me2
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We analyzed the genome-wide chromatin states in Zscan4 positive ES cells (Em+) and Zscan4 negative ES cells (Em-) by using FACS-sorted MC1-ZE7 ES cells. H3K27 hyperacetylation and DNA demethylation were detected in heterochromatic regions of Em+ cells. These results suggested that the heterochromatin is activated in Zscan4 positive state.
Overall design H3K9me2 in Zscan4 positive and negative cells
Contributor(s) Akiyama T, Oda M, Sharav A, Qian Y, Piao Y
Citation(s) 26324425
Submission date Jun 18, 2014
Last update date May 15, 2019
Contact name Minoru S.H. Ko
Phone 410-558-8359
Organization name NIH
Department National Institute on Aging
Lab Lab of Genetics
Street address 251 Bayview Blvd, Suite 100, 10C
City Baltimore
State/province MD
ZIP/Postal code 21224
Country USA
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (2)
GSM1415497 MC1-ZE7 cells (Em-) H3K9me2
GSM1415498 MC1-ZE7 cells (Em+ high fraction) H3K9me2
This SubSeries is part of SuperSeries:
GSE51682 Zscan4 mediates transient remodeling and transcriptional burst of heterochromatin in mouse embryonic stem cells
BioProject PRJNA253030
SRA SRP043374

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Supplementary file Size Download File type/resource
GSE58617_heatmap_H3K9me2.txt.gz 873.8 Kb (ftp)(http) TXT
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