|
| Status |
Public on Jan 01, 2015 |
| Title |
Comparative FAIRE-seq analysis reveals distinguishing features of the chromatin structure of ground state- and primed pluripotent cells |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We utilized FAIRE-seq to identify accesible chromatin in mouse embryonic-, epiblast-, and neural- stem cells in addition to mouse embryonic fibroblasts. Analysis of these data sets reveal cell type specific chromatin signatures that differentiate naïve and primed pluripotency. Functional analysis of type-specific peaks revealed cell-type specific enhancers.
|
| |
|
| Overall design |
FAIRE-seq of mESC, EpiSC, NSC and MEF
|
| |
|
| Contributor(s) |
Murtha M, Dailey L |
| Citation(s) |
25335464 |
| Submission date |
Jun 16, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Matthew Murtha |
| E-mail(s) |
matthew.murtha@nyumc.org
|
| Phone |
2129929171
|
| Organization name |
NYU School of Medicine
|
| Department |
Microbiology
|
| Lab |
Dailey
|
| Street address |
550 First Ave
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10016 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA252824 |
| SRA |
SRP043270 |
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