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| Status |
Public on Jan 01, 2015 |
| Title |
Endogenous germline nuclear RNAi-mediated transcriptional silencing and histone H3 lysine 9 methylation in defined regions of the Caenorhabditis elegans genome |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
We describe the identification and characterization of genomic regions that are targeted by germline nuclear RNAi in C. elegans for transcriptional silencing and heterochromatic response.
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| Overall design |
We compared the wild type and germline nuclear Argonaute protein hrde-1 mutant for their RNA polymerase II ChIP-seq, H3K9 trimethylation ChIP-seq, pre-mRNA seq, mRNA-seq, and small RNA-seq profiles.
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| |
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| Contributor(s) |
Ni JZ, Chen E, Gu SG |
| Citation(s) |
25534009 |
| |
| Submission date |
May 28, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Sam Guoping Gu |
| E-mail(s) |
ggu@dls.rutgers.edu
|
| Organization name |
Rutgers University
|
| Department |
Molecular Biology and Biochemistry
|
| Street address |
604 Allison Road
|
| City |
Piscataway |
| State/province |
New Jersey |
| ZIP/Postal code |
08854 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13657 |
Illumina HiSeq 2000 (Caenorhabditis elegans) |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA248734 |
| SRA |
SRP042338 |
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