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| Status |
Public on Jul 31, 2014 |
| Title |
The effects of phthalates on S. tropicalis development |
| Organism |
Xenopus tropicalis |
| Experiment type |
Expression profiling by array
|
| Summary |
Phthalates are added to polymers in order to increase their flexibility, but leach out of the matrix. Given that these plasticizers are mainly found in water bound to particles, aquatic species are exposed to phthalates. Silurana tropicalis eggs were exposed to high concentrations of three pththalates: dicyclohexyl phthalate (DCHP; 19 mg/L), dimethyl phthalate (DMP; 34 mg/L), and monomethyl phthalate (MMP; 1500 mg/L), along to their respective controls: 0.82% DMSO for DCHP, and water controls for DMP and MMP. The exposure lasted 3 days during embryogenesis. Four pooled of 10 larvae were sampled per treatment and analyzed for gene expression changes using a microarray approach.
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| Overall design |
Four microarrays per group (control and treatment); each phthalate had its on control. There were three phthalates tested that included DCHP, MMP, and DMP.
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| Contributor(s) |
Langlois VS, Mathieu-Denoncourt J, Martyniuk CJ |
| Citation missing |
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| |
| Submission date |
May 14, 2014 |
| Last update date |
Jul 31, 2014 |
| Contact name |
Christopher Joseph Martyniuk |
| E-mail(s) |
CMARTYN@UFL.EDU
|
| Organization name |
UF
|
| Department |
Physiological Sciences
|
| Street address |
CEHT Mowry Road
|
| City |
Gainesville |
| State/province |
FL |
| ZIP/Postal code |
32611 |
| Country |
USA |
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| Platforms (1) |
| GPL15626 |
Agilent-035843 Genotypic_EA519_Xenopus_tropicalis_GE_4x44k |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA247608 |
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