|Public on May 01, 2018
|Phenotypic analysis of conventional knockout mice lacking a protein responsible for ossification of the posterior longitudinal ligament
|Expression profiling by array
|We found disease-specific proteins from serum proteomics of ossification of posterior longitudinal ligament, and made knockout mice.
We discovered protein peculiar to a disease in serum of the ossification of posterior longitudinal ligament (OPLL), and, as a result of producing knockout mouse, we checked spinal ligament ossification and combination of diabetes and thought that it was a typical mouse and analyzed the sequence of the kidney organization.
|Proteomics analysis carried out OPLL of the wild mouse that the ossification of the ligament was confirmed when glucose and urine glucose showed a mouse to the high value from a knockout
|Tsuru M, Nagata K
|May 12, 2014
|Last update date
|May 25, 2018
|Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)