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Series GSE57590 Query DataSets for GSE57590
Status Public on May 01, 2018
Title Phenotypic analysis of conventional knockout mice lacking a protein responsible for ossification of the posterior longitudinal ligament
Organism Mus musculus
Experiment type Expression profiling by array
Summary We found disease-specific proteins from serum proteomics of ossification of posterior longitudinal ligament, and made knockout mice.
We discovered protein peculiar to a disease in serum of the ossification of posterior longitudinal ligament (OPLL), and, as a result of producing knockout mouse, we checked spinal ligament ossification and combination of diabetes and thought that it was a typical mouse and analyzed the sequence of the kidney organization.
 
Overall design Proteomics analysis carried out OPLL of the wild mouse that the ossification of the ligament was confirmed when glucose and urine glucose showed a mouse to the high value from a knockout
 
Contributor(s) Tsuru M, Nagata K
Citation(s) 29782494
Submission date May 12, 2014
Last update date May 25, 2018
Contact name Michiyo Tsuru
E-mail(s) michiyo@med.kurume-u.ac.jp
Phone 81-942-31-7568
Organization name Kurume Universuty
Department Orthopardic Surgery
Street address 67 Asahimachi
City Kurume
State/province Fukuoka
ZIP/Postal code 830-0011
Country Japan
 
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (2)
GSM1385217 wild54
GSM1385218 homo4
Relations
BioProject PRJNA246741

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE57590_RAW.tar 17.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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