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Series GSE57344 Query DataSets for GSE57344
Status Public on Jan 01, 2015
Title RNA-Seq Identifies Novel Myocardial Gene Expression Signatures of Heart Failure [RNA-seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We have utilized the RNA-Seq technology to identify genes with distinct expression patterns between failing and non-failing hearts. In an era of next-generation sequencing studies, our study demonstrates how knowledge gained from a small set of samples with accurately measured gene expressions using RNA-Seq can be leveraged as a complementary strategy to discern the genetics of complex disorders.
Overall design Identify the signature genes based on RNA-seq come from six Heart Failure and healthy individuals. Validation is based on Affymetrix microarray of a total of 313 individuals with/without Heart Failure.
Contributor(s) Liu Y, Morley MP, Brandimarto J, Hannenhalli S, Hu Y, Ashley EA, Tang WH, Moravec CS, Margulies KB, Cappola T, Li M
Citation(s) 25528681, 26134005
Submission date May 06, 2014
Last update date Jun 10, 2019
Contact name Michael Patrick Morley
Phone 215-898-2026
Organization name Perelman School of Medicine at the University of Pennsylvania
Department Penn Cardiovascular Institute
Street address 3400 Civic Center Blvd, Bldg 421
City Philadelphia
State/province PA
ZIP/Postal code 19104
Country USA
Platforms (1)
GPL9052 Illumina Genome Analyzer (Homo sapiens)
Samples (6)
GSM1380718 P01207 Non-failing Left Ventricle
GSM1380719 P01256 Non-failing Left Ventricle
GSM1380720 C00111 Non-failing Left Ventricle
This SubSeries is part of SuperSeries:
GSE57345 RNA-Seq Identifies Novel Myocardial Gene Expression Signatures of Heart Failure
BioProject PRJNA246308
SRA SRP041706

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE57344_RAW.tar 2.1 Mb (http)(custom) TAR (of FPKM_TRACKING)
GSE57344_gene_diff_C02182_C00111.txt.gz 455.0 Kb (ftp)(http) TXT
GSE57344_gene_diff_C02182_P01207.txt.gz 448.3 Kb (ftp)(http) TXT
GSE57344_gene_diff_C02182_P01256.txt.gz 449.5 Kb (ftp)(http) TXT
GSE57344_gene_diff_DCM_vs_NF.txt.gz 492.6 Kb (ftp)(http) TXT
GSE57344_gene_diff_ISCH_vs_NF.txt.gz 470.1 Kb (ftp)(http) TXT
GSE57344_gene_diff_P00234_C00111.txt.gz 471.2 Kb (ftp)(http) TXT
GSE57344_gene_diff_P00234_P01207.txt.gz 470.0 Kb (ftp)(http) TXT
GSE57344_gene_diff_P00234_P01256.txt.gz 469.7 Kb (ftp)(http) TXT
GSE57344_gene_diff_P00333_C00111.txt.gz 459.6 Kb (ftp)(http) TXT
GSE57344_gene_diff_P00333_P01207.txt.gz 457.8 Kb (ftp)(http) TXT
GSE57344_gene_diff_P00333_P01256.txt.gz 458.8 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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