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Series GSE55998 Query DataSets for GSE55998
Status Public on Sep 17, 2014
Title Cellular and Molecular Immune Profiles in Renal Transplant Recipients after Conversion from Tacrolimus to Sirolimus
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Tacrolimus and Sirolimus are commonly used to maintain immunosuppression in kidney transplantation. However, their effects on immune cells and allograft molecular profiles have not been elucidated.
Here we characterized the effects of Tacrolimus to Sirolimus conversion on frequency and function of T cells, and on graft molecular profiles.
Overall design Samples from 30 renal transplant recipients in a randomized trial of late Sirolimus conversion (n=18) vs. Tacrolimus maintenance (n=12) were utilized. Peripheral blood was collected at 0- 6- 12 and 24-months post-randomization. This dataset only contains the 18 arrays corresponding to patients treated with Sirolimus.
Contributor(s) Mas V, Dumur CI, Maluf D
Citation(s) 25354238
Submission date Mar 18, 2014
Last update date Dec 06, 2018
Contact name Catherine Dumur
Organization name Sonic Healthcare USA
Department Anatomic Pathology
Lab Bernhardt
Street address 5008 Mustang Rd
City Jacksonville
State/province FL
ZIP/Postal code 32216
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (18)
GSM1350052 Sirolimus NW_23
GSM1350053 Sirolimus NW_35
GSM1350054 Sirolimus NW_36
BioProject PRJNA242138

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Supplementary file Size Download File type/resource
GSE55998_RAW.tar 55.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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