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| Status |
Public on Feb 17, 2007 |
| Title |
Treatment of cultured human aortic endothelial cells with oligomeric procyanidins extracts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Human aortic endothelial cells were grown in culture until confluent. In three experiments using cells derived from three separate donors confluent cultures were incubated for 6 h with contol medium, or medium containing either extracts of oligomeric procyanidins from cranberry juice or red wine, or a procyanidin-rich grape seed extract. At the end of the 6 h treatment period conditioned media samples were retained for immunoassay of secreted peptides and proteins, and RNA was extracted for microarray analysis.
Keywords: Comparative analysis of procyandins on vascular endothelial gene expression
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| Overall design |
Each experiment used cells from one donor. Treatment conditions were: control medium, cranberry extract (CRE), grape seed extract (GSE), and red wine extract (RWE).
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| Contributor(s) |
Pothecary MR, Lees DM, Khan NQ, Wood EG, Wong JL, Corder R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 17, 2006 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Roger Corder |
| E-mail(s) |
r.corder@qmul.ac.uk
|
| Phone |
+442078826083
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| Organization name |
Queen Mary, University of London
|
| Department |
William Harvey Research Institute
|
| Lab |
Experimental Therapeutics
|
| Street address |
Charterhouse Square
|
| City |
LONDON |
| ZIP/Postal code |
EC1M 6BQ |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA96057 |
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