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Series GSE55043 Query DataSets for GSE55043
Status Public on Feb 15, 2014
Title Dendritic Cell Fate is Determined by BCL11A  
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Here we confirm an essential requirement for the BCL11A transcription factor in fetal pDC development, and for the first time demonstrate this lineage specific requirement in the adult organism. Genome-wide analyses of BCL11A DNA binding and expression revealed that BCL11A regulates transcription of E2-2 and other pDC differentiation modulators including ID2 and MTG16. Our results identify BCL11A as an essential, lineage-specific factor that regulates pDC development.
Overall design ChIP sequenicng was performed for a transcription factor of BCL11A in Cal1 cell line. Input was sequenced and used as a control.
Contributor(s) Tucker H, Iyer V
Citation(s) 24591644
Submission date Feb 14, 2014
Last update date May 15, 2019
Contact name Bum-Kyu Lee
Phone 512-232-8046
Organization name University of Texas at Austin
Street address 2506 Speedway Stop A5000
City Austin
State/province TX
ZIP/Postal code 78712
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (2)
GSM1328451 BCL11A_ChIPSeq
GSM1328452 Input_control
BioProject PRJNA238319
SRA SRP037977

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE55043_RAW.tar 250.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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