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Series GSE54939 Query DataSets for GSE54939
Status Public on Sep 15, 2014
Title Leukocytes methylome of melanoma patients with and without CDKN2A mutations
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary We investigated if the presence of germline CDKN2A mutations or the occurrence of cutaneous melanoma could induce constitutive genome-wide DNA methylation changes. We analyzed the leukocytes’ methylomes of eight patients carrying CDKN2A mutations, eight sporadic melanoma patients and compared them with healthy controls (n=8). The genome-wide DNA methylation profiling was obtained using the Infinium HumanMethylation450 BeadChip platform (Illumina).
Overall design Illumina 450k methylation array profiling performed on melanoma patients carrying germline CDKN2A mutations (n=8), sporadic melanoma patients (n=8) and health individuals (n=8)
Contributor(s) Araújo ÉS, Marchi FA, Rodrigues T, Vieira HC, Kuasne H, Achatz MW, Moredo LF, Sá BC, Duprat JP, Brentani H, Rosenberg C, Carraro DM, Krepischi AV
Citation(s) 25236571
Submission date Feb 12, 2014
Last update date Mar 22, 2019
Contact name Érica Sara Souza de Araújo
Organization name A. C. Camargo Cancer Center
Department CIPE - Internacional Center for Research and Training
Street address Taguá st, 440
City Sao Paulo
State/province Sao Paulo
ZIP/Postal code 01508010
Country Brazil
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (24)
GSM1326822 genomic DNA_CDKN2A-mutation carrier 1
GSM1326823 genomic DNA_CDKN2A-mutation carrier 2
GSM1326824 genomic DNA_CDKN2A-mutation carrier 3
BioProject PRJNA238059

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE54939_RAW.tar 380.8 Mb (http)(custom) TAR (of IDAT)
GSE54939_non-normalized.txt.gz 58.1 Mb (ftp)(http) TXT
Processed data included within Sample table

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