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Series GSE54786 Query DataSets for GSE54786
Status Public on Mar 06, 2014
Title Genome wide localization of chromatin bound NUP98-PHF23 (NP23)
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We analyzed the genome wide localization of H3K4me3, H3K27me3 and the NUP98-PHF23 (with V5 tag) fusion protein which binds H3K4me3 via its PHD finger, using ChIP-seq. Results correlated with gene expression profiles. NUP98-PHF23 bound only 1.6% of H3K4me3 marks including Hoxa/b + Meis1.
Overall design Assess H3K4me3 and H3K27me3 histone marks, and correlate these marks with chromatin binding of the NP23 fusion protein using lymphoblast and myeloblast cell lines derived from NP23 leukemias.
Contributor(s) Gough SM, Yang F, Walker RL, Zhu Y, Pineda M, Bilke S, Meltzer PS, Aplan PD
Citation(s) 24535671
Submission date Feb 07, 2014
Last update date May 15, 2019
Contact name Yuelin Jack Zhu
Phone (240)760-7439
Organization name NCI
Department Genetics Branch, Center for Cancer Research
Lab Dr. Paul Meltzer's Lab
Street address 9000 Rockville Pike
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (13)
GSM1323983 7298-2 H3K27me3
GSM1323984 7298-2 H3K4me3
GSM1323985 7298-2 Input
This SubSeries is part of SuperSeries:
GSE54788 NUP98-PHF23
BioProject PRJNA237651
SRA SRP036859

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Supplementary file Size Download File type/resource
GSE54786_RAW.tar 2.6 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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