|
| Status |
Public on Jan 15, 2014 |
| Title |
Otx2 ChIP-seq in the adult mouse Retinal Pigmented Epithelium (RPE) and neural retina |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Otx2 has been shown to be non cell autonomously required for photoreceptor cell survival in the adult mouse RPE. This study aims to identify Otx2 DNA binding profile in both RPE and neural retina to i) identify direct targets of Otx2 in the RPE ii) compare Otx2 binding profile in neural retina and RPE to unveil hidden functions in the neural retina.
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| |
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| Overall design |
WT and GFP antibodies were used to perform two independent ChIP-seq experiments using Illumina GAIIx.
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| |
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| Contributor(s) |
Lamonerie T, Samuel A, Housset M |
| Citation(s) |
24558479 |
| Submission date |
Jan 14, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Alexander Samuel |
| E-mail(s) |
asamuel@unice.fr
|
| Organization name |
CNRS, INSERM, Université de Nice Sophia-Antipolis
|
| Department |
Institute of Biology Valrose
|
| Lab |
Neurodevelopment
|
| Street address |
Parc Valrose
|
| City |
Nice |
| ZIP/Postal code |
06000 |
| Country |
France |
| |
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| Platforms (1) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA234770 |
| SRA |
SRP035396 |
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